DESCRIPTION:
ZCG 500 by Seeking Health is designed for persons desiring a natural approach to supporting the gastrointestinal lining. ZCG 500 by Seeking Health may be combined with high-quality probiotic formulations -- such as ProBiota 12 by Seeking Health -- for a more comprehensive approach to gastrointestinal healing. ZCG 500 by Seeking Health is a breakthrough in the nutritional support of gastrointestinal health especially in the setting of gastritis, peptic ulcer disease, and intestinal hyperpermeability. ZCG 500 by Seeking Health contains a unique, patented zinc L-carnosine complex that has been clinically shown to promote healing of gastric mucosal lesions. ZCG 500 by Seeking Health also provides L-glutamine, an important energy source for enterocytes and essential nutrient for repairing the intestinal lining and restoring gut barrier integrity. ZCG 500 by Seeking Health is designed for individuals seeking a nutritional approach to preserving healthy gastrointestinal function especially those with a history of gastritis and/or peptic ulceration. ZCG 500 by Seeking Health is formulated to the highest quality standards and is free from common allergens and artificial ingredients. Each vegetarian capsule of ZCG 500 by Seeking Health provides 75 mg of zinc L-carnosine complex (containing 17 mg of elemental zinc) and 400 g of L-glutamine.
BACKGROUND:
The mucosal lining of the gastrointestinal tract provides protection against microbial infection, environmental toxins and allergens, and the erosive effects of its own secretions. Compromise of this mucosal barrier may lead to invasion of pathogenic organisms, increased diffusion of toxic and antigenic substances into tissues, impairment of digestive and absorptive functions, pain, hemorrhage, malignant transformation of cells, and, in more serious cases, death. Disorders associated with damage to the gastrointestinal lining include gastritis, peptic ulcer disease (PUD), and infectious or inflammatory conditions that increase intestinal permeability resulting in what is known as “leaky gut syndrome.”
Gastritis is characterized by mucosal inflammation, infiltration of polymorphonuclear leukocytes (PMNs), lymphocytes, macrophages, and other immune cells, and a decrease in mucosal defense mechanisms. It is a common medical condition often associated with chronic use of non-steroidal anti-inflammatory medications (NSAIDs), alcoholism, and infection with Helicobacter pylori. Less common causes of gastritis include autoimmune disorders, chemotherapy, radiation therapy, excessive stress, bile reflux, viral illness, Crohn’s disease, ingestion of poisons, and direct trauma. Gastritis can be acute or chronic, erosive or non-erosive, symptomatic or asymptomatic, and can affect one or more regions of the stomach.
Gastritis can be a precursor to more serious pathologies such as PUD and gastric cancer. According to some estimates, over ten million new cases of PUD are diagnosed each year. Actual numbers may be much higher as many cases of PUD are asymptomatic and thus go undiagnosed and hence unreported. Originally believed to be a disease of excess acid production, PUD is now largely attributed to H. pylori infection and chronic use of NSAIDs. Despite successful use of H. pylori eradication and acid reduction therapies, PUD remains a major health problem, especially among the elderly where mortality rates associated with bleeding and perforation may reach as high as 17% and 45%, respectively. H. pylori associated gastritis is also the most significant risk factor for gastric cancer. Approximately 20,000 new cases of gastric carcinoma are reported each year in the United States. Unfortunately, most carry a poor prognosis because of late detection.
Leaky gut syndrome is a condition of disrupted intestinal barrier function. The mucosal lining of the intestinal lining is a critical interface between the host and the environment and has been described as an “intelligent” barrier charged with the responsibility of discriminating between self and non-self, and selectively absorbing substances beneficial to the host while barring entry to harmful agents. Many disease states and environmental stressors can compromise the intestinal barrier and lead to impaired function and hyperpermeability. These include infectious or inflammatory gastrointestinal disorders, psychological stress, trauma, burns, surgery, dietary influences, alcoholism, medication use, chemotherapy and radiation, disruption of the intestinal flora, hepatobiliary disease, and aging. These factors alter gut permeability primarily by disrupting normal absorptive pathways through either intestinal epithelial cells (transcellular pathways) or the tight junctions between epithelial cells (paracellular pathways). Once intestinal hyperpermeability is established, continuous entry of harmful substances from the intestinal lumen into the mucosa and beyond can lead to a variety of health conditions: translocation of microorganisms may increase the risk of infection; translocation of proinflammatory substances may cause or exacerbate intestinal or systemic inflammatory disorders; and translocation of antigenic material may give rise to allergic or autoimmune reactions.
Medical management of upper gastrointestinal tract disorders such as gastritis and PUD revolves around pharmacological treatment. In clinical practice, use of antacids, histamine blockers, and proton pump inhibitors often represents first-line therapy. If H. pylori infection is present, eradication procedures utilizing two antimicrobial agents with bismouth and/or a proton pump inhibitor will typically be initiated. Despite these treatments, however, symptoms often persist or return, and H. pylori eradication failure occurs in approximately 20% of patients. Newer acid-reducing agents have also been linked with a burgeoning list of side effects including increased risk for osteoporotic fractures, Clostridium difficile infection, communityacquired pneumonia, and nutrient malabsorption. Currently, conventional medicine offers no treatment approach to leaky gut syndrome.
Deficiencies in the medical management of gastritis, PUD, and altered gut barrier function have led to a need for natural approaches to support gastric and small intestinal health. Zinc L-carnosine and L-glutamine represent two of the most promising natural agents for maintaining the health and integrity of the gastrointestinal lining. Instead of interfering with stomach acid production or destroying bacteria within the gut, these nutraceuticals strengthen gastric and intestinal tissues and enhance their resistance to injury. In animal and human studies, zinc L-carnosine has been shown to exert antiulcerogenic effects and L-glutamine to significantly improve intestinal barrier function. Mounting research on the benefits of these two natural compounds suggests they may be useful alone or as adjuncts for support in a variety of gastrointestinal disorders.
Additional Details of ZCG 500 by Seeking Health
Cost Per Serving: $0.63
Weight:
.2
SKU:
023-05-001-34
Brand:
Seeking Health
Delivery type:
Vegetarian Capsule
Contraindications :
Persons with cirrhosis of the liver, Alzheimer’s disease or manic symptoms, individuals taking penicillamine, antibiotics or methotrexate, and those at higher risk of copper deficiency, such as bariatric surgery patients and users of zinc-based denture cr
Special instructions:
Store in a cool, dry place (59°F-85°F) away from direct light. For long term storage up to two years, the product should be stored at a temperature between 36°F-46°F.
MPN:
023-05-001-34
Return Policy:
45 Day Money Back Guarantee!
Features:
Portable
Made In:
USA
