*Precautions: Please consult with your health care practitioner before using this product. Seek the advice of a physician to ensure a proper successful treatment.  This, and any other supplement, is not a substitute for a qualified caring physician.

What is osteoporosis?

Osteoporosis occurs when bone resorption is faster than bone formation. Bone mass decreases with age and is influenced by sex, race, menopause, and body weight-for-height. Dietary intake of calcium and vitamin D as well as proper intestinal and kidney function affect calcium and phosphate balance. The risk of osteoporosis is highest in postmenopausal women. Asian or white race, underweight, dietary calcium deficiency, sedentary lifestyle, alcohol use, and cigarette smoking are independent risk factors. Decreased vitamin D3 level with aging results in calcium malabsorption, which, in turn, stimulates bone resorption. Estrogen deficiency exacerbates this problem by increasing the sensitivity of bone to resorbing agents. Women who become amenorrheic because of rigorous athletic exercise and dietary restriction or eating disorders are at risk of osteoporosis. The formation and resorption of bone are also influenced by external physical factors such as body weight and exercise. Immobilization and prolonged bed rest produce rapid bone loss, while exercise involving weight-bearing has been shown both to reduce bone loss and to increase bone mass. Osteoporosis is common in young adults with cystic fibrosis, particularly those treated with long-term corticosteroid therapy. The diagnosis of primary osteoporosis is established by documentation of reduced bone density after exclusion of known causes of excessive bone loss. Radiographs are insensitive indicators of bone loss, since bone density must be decreased by at least 20–30% before the reduction can be appreciated. Intake of adequate amounts of calcium and vitamin D, and continuing moderate weight-bearing exercise, are basic preventive measures for persons of all ages. Administration of estrogen at and after menopause does not simply halt the loss of bone, but actually increases bone mass. The hormone calcitonin, administered by injection or nasal spray, inhibits bone resorption and has other effects on mineral metabolism. Strategies to prevent falls are important in elderly patients.

-excerpt from Stedman's Electronic Medical Dictonary,

For the most complete bone density building products, choose OsteoGenesis ES ™ This product is formulated to completely support the maintenance and development of healthy bones. Clinical studies have shown that the ingredients in OsteoGenesis ES™ can actually increase bone density.

Benefits of OsteoGenesis ES™:

• Supports healthy bone density and growth
• Maintains optimal bone health and structure
• Studies have shown the ingredients do increase bone density

Calcium
OsteoGenesis ES™ provides two forms of highly bioavailable calcium. Microcrystalline Hydroxyapatite (MCHA) Calcium is a calcium protein matrix that actually incorporates into bone. MCHA supplies the essential calcium, hydroxyapatite and collagen proteins, glycosaminoglycans, and trace minerals that are essential for a complete bone food.
Calcium Citrate/Malate is considered to be the most soluble and bioavailable form of calcium available. It has been reported to be six times more soluble than either calcium citrate or calcium malate alone. Supplementation reduces risk of post-menopausal bone loss, osteoporosis, and fracture.

Magnesium
In OsteoGenesis ES ™ magnesium is provided in the citrate form only. Magnesium citrate is a highly bioavailable form of magnesium. Magnesium has been shown to regulate active calcium transport and optimize bone response when taken with calcium. Studies have shown that magnesium significantly increases bone density in menopausal women. Magnesium acts as a cofactor in vitamin D hormone activation, and in alkaline phosphatase enzyme formation of bone crystals. Magnesium also contributes to parathyroid hormone regulation.

Vitamin D3 (Cholecalciferol) is the natural form of Vitamin D. It has several beneficial actions on bone metabolism. It is essential in prevention of fractures resulting from osteoporosis and helps prevent bone loss in elderly women. Vitamin D enhances calcium transport across intestinal mucosal cells and enhances osteoblastic bone matrix production. It enhances production of the pro-bone hormone osteocalcin and has regulatory effects on alkaline phosphatase enzyme and collagen protein synthesis. In OsteoGenesis E.S.™ we do not attempt to supply 100% of the RDA of Vitamin D.

Boron improves the metabolism of calcium, phosphorus, and magnesium. It reduces the loss of these minerals through the urine. Boron influences the synthesis of estrogen, Vitamin D, and other steroidal hormones, extending their half-life by protecting them from rapid breakdown. Boron has been shown to increase the tensile strength of connective tissue in bone.

Horsetail (Equisetum arvense) is a natural organic source of water-soluble colloidal silica. Silica strengthens bone matrix connective tissue by enhancing cross-linking of collagen strands. Silica actually concentrates at calcification points of growing bone. Animals fed a silica deficient diet show bone developmental abnormalities.
Zinc, Copper, Manganese, Vanadium and Vitamin C assist in the production of type 1 collagen essential for healthy bone remineralization.