Joint Pain? Take NSAID or Glucosamine?
Glucosamine sulfate has been in the news. Some claiming it bunk and some proving it effective. What does research show? Glucosamine is more effective in providing long term pain relief as compared to other non-steroidal anti-inflammatories (NSAID's). This particular study is attached for you below.
Basically, glucosamine sulfate aids in cartilage rebuilding. NSAID's decrease inflammation and have been shown to inhibit cartilage formation. So - long term benefit is definitely going to be providing nutrients allowing your joints to recover. Decreasing inflammation is important but removing the cause of inflammation is more important. Obviously not all causes can be removed but multitudes indeed can be stopped.
Taking plain glucosamine sulfate is useful. However, if one wants to completely rebuild a joint properly, the aggravating factors must be addressed. This is where your physician comes in handy. Have them properly diagnose and educate you on what the cause of your condition is - not only the name of the condition - what caused it?!
Once the cause is addressed, physical therapy and nutrionals are needed. As a medical student, I have the ability to mingle with known physicians in our field. One such physician is Dr David Wood, founder of Biogenesis Nutraceuticals. He has formulated a product called ArthroGenX that has helped my wife with her Rheumatoid Arthritis. Our roofer since found it useful as well. He stated he could not sleep at night due to pains in his hands. I tossed a bottle of ArthroGenX up to him on the roof and suggested he take 2 capsules. He repeated the dose that evening before sleep and sleep had set in. Why does it work so fast?
ArthroGenX has built in herbals which decrease inflammation and improve absorption of the cartilage rebuilding ingredients. The ingredient listing of ArthroGenX and description can be found on its page. We have a full page dedicated to each product on our site as we want to educate the public - you - on why that product is useful and what is in it.
Should you have joint pain, please consult with a trusted physician and learn about the cause of your condition. We are here to help provide useful information and products.
Please consider ArthroGenX for your joint pains.
Any questions regarding joint pain and stiffness, please post a comment or email us directly.
In health,
Ben
Glucosamine and Ibuprofen study
PS - www.pubmed.com is a very useful source for finding any current medical research on just about anything.
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2 Comments:
hi Ben!
wanted to put some input in regard to use of glucosomine...and see if you agree--from your experience and education:
put my husband on it--and for the first time---his labwork came back with a high sugar reading--indicative of diabetes.
i then came across what seemed to be authentic warning info--regarding blood sugar levels being elevated with glucosomine use/diabetics not to use!.....
naturally, took him off it...:)
..and he has never had another abnormal / high blood sugar level.
***another tidbit---for diabetics...that we personally know 3 people who use fresh or dried parsley--and by using===delivered themselves from diabetic state...and are free now of diabetes and need for intervention with insulin,etc.
***parsley virtually doesn't have much taste....and is user friendly.
my husband uses it even on his oatmeal in the morn's....as well as his dinner meal,etc.----as he is being preventative....as his brother has diabetes for last 5 years...and they are close in age.
best regards, Ben:)
---Pam [adrenal...lol] from michigan
In looking at various studies out there, I found this one - yet one must always question research as statistics can always be manipulated for desired results. One must look at who funded the research and how was it it setup? Take for example the latest on Vitamin E - stating that it is harmful. I cannot begin to tell you how many doctors came running together, sourced good research and put that scientist in a place of shame.
I will research glucosamine/blood sugar further as I would like to know if there is truely a connection. At first glance, I would say that your husband must have already been susceptible and with risk factors for type II before taking glucosamine. However, I do not disregard your comments. With type II diabetes being the fastest growing disease today, many things will be blamed for its cause.
The main causes of type II: stress, poor diet, obesity, genetics, soft drinks, lack of exercise.
One study I found:
The effect of glucosamine-chondroitin supplementation on glycosylated hemoglobin levels in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial.
Scroggie DA, Albright A, Harris MD.
Department of Rheumatology, 59th Medical Wing, Wilford Hall Medical Center, Lackland Air Force Base, Lackland, TX 78236, USA. Daren.Scrogie@lackland.af.mil
BACKGROUND: With increasing use of glucosamine-containing supplements for the treatment of osteoarthritis, there is increasing concern in the medical community about possible toxic effects. The present study was undertaken to determine whether glucosamine supplementation altered hemoglobin A1c concentrations in patients with well-controlled diabetes mellitus. OBJECTIVE: To evaluate possible effects of glucosamine supplementation on glycemic control in a selected population of patients with type 2 diabetes mellitus. DESIGN: Placebo-controlled, double-blinded, randomized clinical trial. SETTING: Outpatient, diabetes monitoring clinic. PATIENTS: Patients were typically elderly patients, evenly divided between men and women. Most of the patients were being treated with 1 or 2 drugs for glycemic control. INTERVENTION: In daily doses for 90 days, patients received either placebo or a combination of 1500 mg of glucosamine hydrochloride with 1200 mg of chondroitin sulfate (Cosamin DS; Nutramax Laboratories Inc, Edgewood, Md).Main Outcome Measure Hemoglobin A1c levels before and after 90 days of therapy. RESULTS: There were 4 withdrawals from the glucosamine-treated group. Three were related to comorbidities (myocardial infarction, congestive heart failure, and atrial fibrillation) and 1 to a possible adverse reaction (excessive flatus). No other patient reported any adverse effects of glucosamine therapy, and no patient had any change in their diabetes management. Mean hemoglobin A1c concentrations were not significantly different between groups prior to glucosamine therapy. Posttreatment hemoglobin A1c concentrations were not significantly different between groups, nor were there any significant differences within groups before and after treatment. CONCLUSION: This study demonstrates that oral glucosamine supplementation does not result in clinically significant alterations in glucose metabolism in patients with type 2 diabetes mellitus.
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With regards to parsley: Type II diabetes can be reversed with many interventions - diet being a major player. If one is willing and wanting to change dietary habits, then type II will likely reverse.
Parsley is a strong alkaline plant with liver protective qualities.
Effects of parsley (Petroselinum crispum) on the liver of diabetic rats: a morphological and biochemical study.
Bolkent S, Yanardag R, Ozsoy-Sacan O, Karabulut-Bulan O.
Department of Biology, Faculty of Science, Istanbul University, 34459-Vezneciler, Istanbul, Turkey.
Parsley is used by diabetics in Turkey to reduce blood glucose. The present study aims to investigate both the morphological and biochemical effects of parsley on liver tissue. Rat hepatocytes were examined by light and electron microscopy. Degenerative changes were observed in the hepatocytes of diabetic rats. These degenerative changes were significantly reduced or absent in the hepatocytes of diabetic rats treated with parsley. Blood glucose levels, alanine transaminase and alkaline phosphatase were observed to be raised in diabetic rats. Diabetic rats treated with parsley demonstrated significantly lower levels of blood glucose, alanine transaminase and alkaline phosphatase. The present study suggests that parsley demonstrates a significant hepatoprotective effect in diabetic rats. 2004 John Wiley & Sons, Ltd.
Thank you for your comments, Pam! Great sharing these points.
In health,
Ben
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